Posters

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P1 – Investigating the Mg2+ cations influence on the formation of RNA Kissing complexes

Josephine Abi-Ghanem1,2,3, Clémence Rabin1,2,3, Massimiliano Porrini1,2,3, Valérie Gabelica1,2,3

 

P2 – From DNA Computation to Aptamer Selection: Beyond the Hopfield approximation.

Dr. Jean-Pierre Aimé, Dr Juan Elezgaray.

 

P3 – Aptaswitches: new supramolecular tools

  1. Bonnet-Salomon, E. Dausse, G. Durand, J.-J. Toulmé and L. Azéma

 

P4 – Targeted anticancer therapy using bioconjugates of magnetic nanoparticles with DNA-aptamers

Irina.V. Belyanina1,2,3, Anna Zamay1,2, Galina S. Zamay1,2, Yury E. Glazyrin2, Olga S. Kolovskaya1,2, Taiana Ivanchenko1, Dmitry Veprincev1,2, Alexey E. Sokolov1, Valery Denisenko1, Sergey Zamay1, Maxim Berezovski4, scientific adviser dr. Tatiana N. Zamay

 

P5 – Development of synthetic riboswitches.

Adrien Boussebayle, Thea Lotz, Beatrix Süß.

 

P6 – An Aptamer-Based Diagnostic Test Specific for Falciparum Malaria

Yee-Wai Cheung1, Roderick M. Dirkzwager1, Josiane Cardoso2, Alvin Wai-Chung Wong1 and Julian A. Tanner1

 

P7 – RNA aptamers as ligands of integrin alpha5 beta1

Marine Fenat1, Pierre Fechter2, Nelly Etienne-Selloum1, Isabelle Lelong-Rebel1, Sophie Martin1, Maxime Lehmann1, Monique Dontenwill1 & Laurence Choulier1

 

P8 – ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform

Benoit Chovelon,1,2 Guillaume Durand,3 Eric Dausse,3 Jean-Jacques Toulmé,3 Patrice Faure,2,4 Eric Peyrin1* and Corinne Ravelet1*

 

P9 – Near infrared fluorescent imaging for aptamers biodistribution

Ioanna Theodorou1,2, Chloé Dambrune1,2, Nam Nguyen Quang1,2, Benoit Lelandais1,2, Frederic Ducongé1,2

 

P10 – Identification of DNA kissing complexes.

Eric Dausse, Nicolas J. Tourasse and Jean-Jacques Toulmé

 

P11 – Riboswitches based on kissing complexes for the detection of small ligands

Durand Guillaume1,2, Eric Dausse2, Corinne Ravelet3, Eric Peyrin3, Jean-Jacques Toulmé2,4

 

P12 – Riboswitch – Small Molecule Interactions Analyzed with the switchSENSE Platform

Felix Kroener1,2, Christopher Schneider3, Florian Groher3, Beatrix Süß3, Wolfgang Kaiser1

 

P13 – A novel internalizing Aptamer Targeting Insulin Receptor

Margherita Iaboni 1,4, Raffaela Fontanella2, Anna Rienzo3, Maria Capuozzo3, Nuzzo S.1, 3, Silvia Catuogno3, Gerolama Condorelli 1,3, Vittorio de Franciscis3, Carla Lucia Esposito3

 

P14 – Single cell-level microsurgery using aptamer functionalized magnetic microdiscs for tumor eradicationIrina Garanzha, a,c, Anna Zamaya,b, Galina S. Zamaya,b, Yury E. Glazyrinb, Olga S. Kolovskayaa,b, Alexandr Shabanova, Viktor Y. Prinze, Vladimir Selezneve, Tatiana Ivanchenkob, Dmitry Veprinceva,b, Alexey E. Sokolova, Valery Denisenkoa, Sergey Zamaya, Ana Gargaund, Maxim Berezovskid, scientific adviser dr. Tatiana N. Zamay

 

P15 – Colorimetric small molecules sensing using a structure switching strategy on modified gold nanoparticles

Emma Goux1, Valérie Guieu1*, Luc Choisnard1, Guillaume Durand2, Eric Dausse2, Jean-Jacques Toulmé2, Corinne Ravelet1 and Eric Peyrin1

 

P16 – Kinetic analysis of the different candidate RNA aptamers-protein interactions

Nathalie Vollmer1, Karen Mercier1, Fatima-Ezzahra Hibti1, Xianbin Yang2, Mark Shumbera2, Marinella Sandros3, Chiraz Frydman1

 

P17 – Subtractive cell SELEX for DNA aptamers binding to a human leukemia cell line.

NA Kacherovsky1, BR Olden1, SJ Salipante2, MC Jensen3, SH Pun1

 

P18 – Nuclease-Activated Oligonucleotide Probes for the Rapid and Robust Detection of Breast Cancer Circulating Tumor Cells (CTCs)

Sven Kruspe1, David D. Dickey1, William H. Thiel1, Karen C. Clark1, Kevin Urak2, Elliot Burghardt1, Justin P. Dassie1, Alexandra Thomas1, James O. McNamara II1,2, Paloma H. Giangrande1,2,3.

 

P19 – Quantification of non-coding RNAs in bacterial cells

using a Broccoli aptamer

Charlotte Hardion, Alexandre Dawid, Stéphan Lacour

 

P20 – The skin: a novel field for therapeutic aptamers

Thomas Lettner, Julia Reichelt, Verena Wally.

 

P21 – Development of aptamer-based electrochemical sensing system for monitoring luteinizing hormone pulsatility

Shaolin Liang1, 2, Waljit Dhillo2, Anthony E G Cass3 and Julian A Tanner1

 

P22 – Aptamers Binding To Bradykinin

Ricardo Lima Pereira, Arquimedes Cheffer, Claudiana Lameu, Ana Paula Santos, Henning Ulrich

 

P23 – CE-non-SELEX for the isolation of aptamers directed against the tau protein.

Samuele Lisi1,2, Emmanuelle Fiore1, Yannik Boehmann3, Simona Scarano2, Maria Minunni2, Eric Peyrin1, Corinne Ravelet1

 

P24 – Experimental conditions affect apparent affinity of thrombin-binding DNA aptamers

Kepler Mears1, Delia J. Scoville1, Rebecca J. Whelan1

 

P25 – MicroScale Thermophoresis: Interaction Analysis and beyond

Moran Jerabek-Willemsen, Timon André, Randy Wanner, Heide Marie Roth, Stefan Duhr, Philipp Baaske, Dennis Breitsprecher

 

P26 – Identification of Stem Cell Lung Cancer by DNA Aptamers

Isis C. Nascimento1, Jan Mavri2, Tina Smuc2, Arthur A. Nery1, Tamara T. Lah3, Matjaz Peterka2, Henning Ulrich1

 

P27 – Selection of Specific, Slow Off-rate Modified Aptamer (SOMAmer®) Reagents for the Highly Similar Proteins GDF-11 and GDF-8

Urs Ochsner1, Louis Green1, Taylor Rice1, and Nebojsa Janjic1

 

P28 – An RNA aptamer that binds the glycolytic flux-signaling metabolite

Fructose-1,6-bisphosphate.

Alvaro D. Ortega1, Yi Long2, Neus Mestre-Farràs1, Franziska Pfeiffer3, Günter Mayer3, Lars Folke Olsen2, Matthias Heinemann1.

 

P29 – Targeting CD28 costimulation with bi-specific aptamers to melanoma chemotherapy resistant cancer stem cells.

Mario M Soldevilla1,2, Helena Villanueva1,2, Noelia Casares2,3, Juan J Lasarte2,3, Maurizio Bendandi4, Susana Inoges2,5, Ascension López-Díaz de Cerio2,5, Fernando Pastor1,2.

 

P30 – Preclinical trials of novel anticoagulant — DNA aptamer Trombiveb®.

Galina V. Pavlova1,2, Alexey M. Kopylov1,3, Askar D. Turashev1, Nadezhda S. Samoylenkova1,2, Elena G. Zavyalova1,3, Alexander V. Revishchin2, Andrey V. Golovin1,4.

 

P31 – Biophysical characterization of RNA-metabolite complexes by native MS

Stefano Piccolo 1,2,3 et Valérie Gabelica 1,2,3

 

P32 – Semi-automated binding of aptamers on adherent living cells

Nam Nguyen Quang1, 2, Carine Pestourie3, Agnès Cibiel4 & Frédéric Ducongé1, 2,*

 

P33 – PATTERNITY-seq: high-throughput analysis of sequence patterns and paternity relationship between them during molecular evolution processes.

Nam Nguyen Quang1,2, Clément Bouvier1,2, Benoit Lelandais1,2 and Frédéric Ducongé1,2.

 

P34 – A native MS Study of RNA kissing complexes and their interaction with magnesium cations

Clémence Rabin 1,2,3, Adrien Marchand1,2,3, Joséphine Abi-Ghanem1,2,3 & Valérie Gabelica1,2,3

 

P35 – Functional neutralization of αC-conotoxin PrXA by aptamers

Tarek Mohamed Abd El Aziz1, 3, Corinne Ravelet2* , Emmanuelle Fiore2 , Germain Sotoing Taiwe5, Michel Ronjat1, Jerôme Dejeu4, Eric Peyrin2, , Michel De Waard1, 6

 

P36 – Aptamers for identification and purification of mesenchymal stem cells

Ana Paula Santos; Arthur A. Nery; Henning Ulrich1

 

P37 – Selection of aptamers against the norovirus protruding domain in presence of four different food matrices

Katja Schilling1,2, Jacquelina Woods2

 

P38 – Characterization of aptaswitch complexes by MicroScale Thermophoresis.

Thomas Schubert, Eric Dausse2, Kniep Lukas1, Guillaume Durand2, Jean-Jacques Toulmé2.

 

P39 – Selecting DNA Aptamers for the Ovarian Cancer Biomarker CA125

Delia Scoville1, Tae Kyu Brian Uhm1, Jamie Shallcross1, Rebecca Whelan1

 

P40 – Aptamer-Mediated Macromolecular Recognitionin Facilitating DNA Tweezer Machinery

Simon Chi-Chin Shiu, Yee-Wai Cheung, Roderick M. Dirkzwager, Shaolin Liang,

Andrew B. Kinghorn, Lewis A. Fraser, Marco S. L. Tang and Julian A. Tanner

 

P41 – Efficient Cell-SELEX using engineered isogenic cell lines to generate RNA aptamer against a cell surface protein of interest

Masaki Takahashi1, Yoshifumi Hashimoto1, Eri Sakota1, Yoshikazu Nakamura1,2

 

P42 – Aptamer-gated DNA origami nanobox for malaria detection

Marco S. L. Tang1, Maia Godonoga2, Andrew B Kinghorn1, Yee-Wai Cheung1, Jonathan Heddle3

and Julian A. Tanner1

 

P44 – Control of pre-mRNA splicing by the tetracycline aptamer

Marc Vogel1, Julia E. Weigand1, Beatrix Süß1

 

P45 – Multiplex aptamer-based electrochemical sensor for lung cancer detection.

Galina S. Zamay1,2, Yury E. Glazyrin1,2, Tatiana N. Zamay1, Vasilii A. Kolovsky7, Alexandr V. Shabanov3, Dmitry V. Veprintsev1, Alexey V. Krat4, Sergey S. Zamay3, Olga S. Kolovskaya1, Ana Gargaun6, Alexey E. Sokolov5, Andrey A. Modestov4, Ivan P. Artyukhov1, Nikolay V. Chesnokov2, Marina M. Petrova1, Maxim V. Berezovski6, Anna S. Zamay*1,2  

 

P46 – Selective elimination of tumor cells in vivo using laser induced plasmon resonance of aptamer functionalized gold nanoparticles

Tatiana. N Zamaya,b, Irina.V. Belyaninab,d, Alexandr Alexandrovskiia, Alexey E. Sokolova, Dubinina Annaa, Galina S. Zamaya,b, Irina Garanzhad, Yury E. Glazyrinb, Olga S. Kolovskayab, Tatiana Ivanchenkob, Natalia Chanchikovac, Nikolay Tokarevc, Nikolay Shepelivichc, Elena Karlovac, Anastasia Ozerskayac, Evgeniy Badrinc, Kirill Beluginc, Semion Belkinc ,Vladimir Zabludaa, Maxim Berezovskie, Anna Zamayb

 

P47 – INTERFERING WITH THE PROLIFERATION OF PLASMODIUM FALCIPARUM BY CELL-SELEX

Flávia Zimbres1, Henning Ulrich2, Carsten Wrenger1

 

P48 – Generating aptamers capable of binding small molecular targets and refining the target binding characteristics

Shalen Kumar1,2, Shiwei Li1,2, Jeremy Jones1, Doug C. Eckery3, Janet Pitman1 and Kenneth P. McNatty1

 

P49 – Identification of glioblastoma stem-like cells by DNA aptamers

Erika de S. Molina1, Tiago Sobreira2, Marina Trombetta-Lima3, Lucas Nishida1, Maria Elisa Goes1, Attila Tárnok4, Heidrun Holland4, Isis C. Nascimento1, Mari Cleide Sogayar3, Henning Ulrich1

 

P50 – Use of aptamers as antitumor agents based on Cell Selex methodology for prostate cancer

Aline Moreira1, Anael Alberto1, Helena Magalhães1, Leila Mendonça1, Etel Gimba2, Martin Bonamino3,4, Wim Degrave1 and Mariana Waghabi1

 

P51 – Conditional aptaswitch interaction.

Lorena Zara1, Eric Dausse1, and Jean-Jacques Toulmé1,2

 

P52 – Switch Aptamers-Based Analysis: A Promising Alternative for Mycotoxins Detection

Gaëlle Catanante1, Atul Sharma2, K. Yugender Goud3, and Jean-Louis Marty1

 

P53 – Aptamer selection by microfluidic recovery coupled with SPR detection

Carmelo Di Primo1,2, Eric Dausse1,2, Aurélien Barré3, Alain Rico4, Emilie Daguerre1,2, Gilmar Salgado1,2, Macha Nikolski3 and Jean-Jacques Toulmé1,2

 

P54 – Just in Time-Selection: A semiautomated two-step method for in vitro selection of DNA aptamers
Fischer

 

P55 – Tunable Cytotoxic Agents for the Treatment of Prostate Cancer

Bethany Powell Gray1, Linsley Kelly2, Jessica McDade1, Matthew Levy2, and Bruce A. Sullenger1,3

 

P56 – Fluid Biopsy Allowing Lung Cancer Diagnosis via Aptamer Based CTC Detection

V.L. Grigoreva1,3, Galina S. Zamay1,2, Anna Zamay1,2 , Yury E. Glazyrin2, Olga S. Kolovskaya1,2, Alexey V Krat1,2, Irina Garanzha1,3, Ana Gargaun4, Marina Petrova2, Ivan Artyukhov2, Maxim Berezovski4, scientific adviser dr. Tatiana N. Zamay

 

P57 – Active and Exo-site Inhibition of Factor Xa by RNA Aptamer-Drug Pairs for Potent, Reversible Anticoagulation

Ruwan Gunaratne1, James Frederiksen1, Michelle D. Ho2, Nabil K. Thalji2, Rodney M. Camire2, and Bruce A. Sullenger1

 

P58 – Small-Molecule Detection and Enantiopurity Measurement Using DNA-Based Sensors.

Jennifer Heemstra1, Trevor Feagin1, Amberlyn Peterson1, and Zhesen Tan1

 

P59 – Expanding the Chemical Diversity of DNA

Chun Guo1, Dehui Kong1, Yi Lei1, and Ryan Hili1

 

P60 – DNA-aptamers as synthetic molecular probes for staining of abnormal blood vessels and tumor cells in lung cancer tissue sections

Olga S. Kolovskaya1,2, Galina S. Zamay1,2, Tatiana Ivanchenko2, Tatiana N. Zamay1, Valentina Grigorieva1, Maxim V. Berezovski3, and Anna S. Zamay1,2

 

P61 – Fitness Landscapes of Functional RNAs

Ádám Kun1,2,3 and Eörs Szathmáry1,3,4

 

P62 – FNA fluorescence reporting within silica-zirconia porous thin films

Marine Le Goas1, Nina Landreau1, Valérie Guieu2, Corinne Ravelet2, Eric Peyrin2, Serge Palacin1 and Laurent Mugherli1

 

P63 – Asymmetric inhibition of a small chiral molecule/aptamer binding reaction upon aptamer modification: a kinetic study using rotating droplet electrochemistry

Lylian Challier1‡, Rebeca Miranda-Castro1‡, Claire Fave2, Benoît Limoges2, François Mavré2, and Vincent Noël1

 

P64 – Selection of DNA aptamers from libraries of G-rich sequences as potential therapeutic agents in HMGB1-related pathologies

Domenica Musumeci1,3, Carla L. Esposito2, Giovanni N. Roviello3, Angela Coppola1, Vittorio De Franciscis2, Claudia Riccardi1, Chiara Platella1, and Daniela Montesarchio1

 

P65 – Ultrasensitive and rapid detection combining aptamers and isothermal recombinase polymerase amplification

Miriam Jauset-Rubio1, Markéta Svobodová1, Teresa Mairal1, Mohammad S. El-Shahawi3, Abdulaziz S. Bashammakh 3, Abdulrahman O. Alyoubi3, and Ciara K. O´Sullivan 1,3

 

P66 – Small Molecule Aptamer Assays Based on Fluorescence Anisotropy Signal-Enhancer Oligonucleotides

Sandrine Perrier, Prisca Bouilloud, Gisella De Oliveira Coelho, Mickael Henry and Eric Peyrin

 

P67 – Strategy of enhanced fluorescence polarization based on aptamer – protein anchor complexes for sensitive and rapid detection of ochratoxin A

Irina V. Safenkova1, Alexey V. Samokhvalov1, Sergei A. Eremin2, Anatoly V. Zherdev1, and Boris B. Dzantiev1

 

P68 – Targeting Structured RNAs via Cross-Chiral Recognition

Jonathan T. Sczepanski1

 

P69 – Development of an Antidote-Controlled RNA Probe for Molecular Thrombi Imaging

Kady-Ann Steen-Burrell1, Bethany Powell Gray1, and Bruce Sullenger1