Final programme

Password required (provided upon meeting registration)

Friday June 28th

8:20

Registration opening

SESSION I

08:30 – 08:50

O1 : J. Attwater

Emergence of cooperativity during in vitro selection of a self-synthesising ribozyme

MRC, Cambridge, UK

08:50 – 09:10

O2 : F. Bernard

Full-length analysis of Caenorhabditis elegans transcriptome using Nanopore sequencing technology

Univ. Bordeaux, France

09:10 – 09:30

O3 : J. Wachtveitl

Structure guided fluorescence labeling reveals a two-step binding mechanism of neomycin to its RNA aptamer

Goethe Univ, Frankfurt, Germany

09:30 – 09:50

O4 : P. Johnson

Fine-tuning the binding affinity of a structure-switching aptamer using dangling nucleotides

York Univ., Toronto, Canada

09:50 – 10:30

O5 : J. Lieberman KEYNOTE

Aptamer delivery of siRNAs to knockdown cancer

Harvard Medical School, USA

Coffee Break

SESSION II

11:10 – 11:30

O6 : M. Sunbul

Genetically Encoded Light-up Aptamers for Live-cell Super-resolution RNA Imaging

Heidelberg Univ, Germany

11:30 – 11:50

O7 : A. Sett

Light-up Aptamers – A tool for the detection of small molecules and biological ligands

Univ. Bordeaux, France

11:50 – 12:10

O8 : F. Bouhedda

Evolution of efficient RNA-based fluorescent probes using ultrahigh- throughput functional screening

Univ Strasbourg, France

12:10 – 12:30

O9 : O. Puchta

High-throughput screening of fluorescent RNA aptamers

Univ. Edinburgh, UK

Lunch

SESSION III

14:00 – 14:20

O10 : V. Guieu

Single-Stranded DNA Binding Protein-Assisted Fluorescence Polarization Aptamer Assay: generalization to an unstructured aptamer

Univ Grenoble-Alpes, France

14:20 – 14:40

O11 : B. Suess

A TetR-binding aptamer as versatile regulatory element

U. Darmstadt, Germany

14:40 – 15:00

O12 : F. Ducongé

How to redirect molecular evolution when it goes in the wrong direction

CEA, France

15:00 – 15:20

O13 : B. Olave

First DNA-aptamers specific to non-physiological media. A SELEX towards ATP in ionic liquid 

Univ Basque Country, Donostia-San Sebastian, Spain

15:20 – 15:40

O14 : C. K. O’Sullivan

One-pot SELEX: simultaneous selection of specific aptamers against diverse steroid targets

Univ Rovira I Virgili, Tarragona, Spain

Coffee Break

16:20 – 18:00

Poster session & refreshment break

See list of posters

From 20:00

Gala dinner*

Le Sicambre, Ponton “River Cruise” (upon invitation)

Saturday June 29th

SESSION IV

08:30 – 08:50

O15 : P. M. Jurek

Development and characterization of a chemically modified DNA aptamer against a T-cell exhaustion marker using the PureAptaTM platform

Pure Biologics, Poland

08:50 – 09:10

O16 : P. R. Mallikaratchy

Integrating ligand receptor interactions and in vitro evolution for streamlined discovery of artificial nucleic acid ligands against T-Cell receptor-CD3 Complex in human T-cells

Lehman College, USA

09:10 – 09:30

O17 : I. Rusinek

De novo discovery of tumoricidal aptamers in a DNA sequencing chip

Augmanity, Israel

3, The Colombo Plan

4, U.S. Drug Enforcement Administration, Educational Foundation

09:30 – 09:50

O18 : G. Mayer

Optoribogenetics to control cellular process

U. Bonn, Germany

09:50 – 10:30

O19 : M. Famulok KEYNOTE

Interlocked DNA nanostructures for molecular engineering

U Bonn, Germany

Coffee break

SESSION V

11:10 – 11:30

O20 : D. Brennan

A DNAzyme-based Colorimetric Paper Sensor for Helicobacter pylori.

McMaster Univ, Hamilton, Canada

11:30 – 11:50

O21 : V. Lucarelli

Development of a novel aptamer-based biosensor to detect invasive mammal pests

U. Auckland, New Zealand

11:50 – 12:10

O22 : J.A. Tanner

Evolution, Crystal Structure, and Application of Cubane-Modified Aptamers – “Cubamers” – for Malaria Diagnosis

U. Hong-Kong, China

12:10 – 12:30

O23 : L. Choulier

RNA aptamers targeting integrin α5β1 as probes for cyto- and histo-fluorescence in glioblastoma

Univ Strasbourg, France

Lunch & Posters

SESSION VI

14:00 – 14:20

O24 : N. Kacherovsky

Traceless aptamer-mediated isolation of CD8+ T cells for CAR T cell therapy

U. Washington, USA

14:20 – 14:40

O25 : D. Rana

Towards Controlling Vascularization within Engineered Tissues via Programmable Hydrogels

U. Twente, The Netherlands

14:40 – 15:00

O26 : V. De Franciscis

Aptamers for the selective targeting of therapeutic RNAs

CNR, Italy

15:00 – 15:20

O27 : M. Hernández-Jiménez

ApTOLL, filling the gap of therapeutic molecules in ischemic stroke treatment

Apta Targets, Spain

2, Department of Chemistry, Department of Physiology and Functional Genomics Center for Research at Bio/nano Interface, Moffitt Cancer Center and Shands Cancer Center, University of Florida, Gainesville, FL 32611, USA

15:20 – 15:40

O28 : B. Sullenger

Aptamers as reversible ligands for therapeutic, imaging and clean cell purification applications.

U. Durham, USA

Coffee Break & Poster Awards

SESSION VII

16:20 – 17:00

O29 : Maria DeRosa KEYNOTE

Aptamers as tools for the study and treatment of Parkinson’s Disease

Carleton University, Canada

17:00 – 17:20

O30 : F. Pastor

ICOS costimulation at the tumor site in combination with CTLA-4 blockade therapy elicits antitumor immune responses

Univ Navarra, Pampelona, Spain

17:20 – 17:40

O31 : P. Giangrande

Inhalation of an RNA Bio-drug Targeting Extracellular Histones Protects from Acute Lung Injury

U. Iowa and Moderna, USA

17:40 – 18:00

O32 : L. Gold and N. Janjic

SOMAmers and SOMAscan: Molecular Snuggling and Binding Specificity

SomaLogic, USA